A 35-year-old man with subacute infective endocarditis has tender nodules on the pads of his fingers and painless hemorrhagic macules on his palms. These two findings respectively represent:
- A Osler nodes and Janeway lesions ✓
- B Janeway nodes and Osler lesions
- C Roth spots and Osler nodes
- D Janeway lesions and Roth spots
Correct answer: A. Osler nodes and Janeway lesions
Explanation
Osler nodes are tender, raised lesions on finger and toe pads caused by immune complex deposition with microabscesses, while Janeway lesions are painless erythematous hemorrhagic macules on palms and soles caused by septic microemboli. Roth spots are retinal hemorrhages with pale centers seen on fundoscopy, not on skin. Distinguishing painful immunologic manifestations from painless embolic ones is a standard examination point in infective endocarditis.
Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.