Orthopedics · Peripheral Nerve Injuries

A nerve injury in which the axon and myelin sheath are disrupted but the endoneurium is intact is classified by Seddon's classification as:

  • A Neuropraxia
  • B Neurotmesis
  • C Neurapraxia with demyelination only
  • D Axonotmesis
Correct answer: D. Axonotmesis

Explanation

Seddon's classification divides nerve injuries into three types: neuropraxia (conduction block only, axon and sheath intact — full spontaneous recovery), axonotmesis (axon disrupted, endoneurium intact — Wallerian degeneration occurs but regeneration along intact endoneurial tubes is possible at 1 mm/day), and neurotmesis (complete division of nerve — surgical repair required). Axonotmesis is the most common significant peripheral nerve injury.

Reference: Maheshwari Essential Orthopaedics, 6th ed.

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