An orthopedic surgeon is evaluating an enchondroma versus a low-grade chondrosarcoma of the phalanx. Which feature MOST strongly favors low-grade chondrosarcoma over enchondroma in the short bones of the hand?
- A Asymptomatic lesion
- B Lesion less than 3 cm
- C Pain associated with the lesion ✓
- D Well-circumscribed lesion with calcifications
Correct answer: C. Pain associated with the lesion
Explanation
In short tubular bones of hands and feet, enchondromas are common and usually asymptomatic. Pain associated with a cartilaginous lesion in this location strongly suggests low-grade chondrosarcoma rather than benign enchondroma. Enchondromas in hands are typically small, well-defined, and painless. Size and calcifications alone do not reliably distinguish benign from malignant in small bones.
Reference: Campbell's Operative Orthopaedics, 14th ed.
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