Excluding plasma cell myeloma, which is the most common primary malignant tumour of bone?
- A Ewing sarcoma
- B Chondrosarcoma
- C Osteosarcoma ✓
- D Primary bone lymphoma
Correct answer: C. Osteosarcoma
Explanation
Plasma cell myeloma is the most common primary malignant bone tumour overall, followed by osteosarcoma in second place. Osteosarcoma peaks in adolescence around the knee but has a documented second peak in elderly patients with pre-existing conditions such as Paget disease or prior irradiation. Chondrosarcoma ranks third and affects an older age group, while Ewing sarcoma is far less common than both.
Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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