In the Enneking staging of musculoskeletal tumors, a Stage IIB lesion is defined as:
- A High-grade tumor that has extended beyond the compartment (extracompartmental) ✓
- B Low-grade tumor confined within the compartment (intracompartmental)
- C High-grade tumor confined within the compartment (intracompartmental)
- D Any grade tumor with regional or distant metastasis
Correct answer: A. High-grade tumor that has extended beyond the compartment (extracompartmental)
Explanation
Enneking staging combines histological grade (I = low, II = high) with anatomical site (A = intracompartmental, B = extracompartmental) and metastasis (Stage III = any grade with metastasis). Stage IIB = high-grade malignant tumor that has breached the natural anatomical barrier (fascia, periosteum, cortex) and extended extracompartmentally — these require wide resection margins. Stage IIA = high-grade intracompartmental. Stage III carries the worst prognosis regardless of compartmental status. Enneking staging guides margin requirements for surgery.
Reference: Maheshwari Essential Orthopaedics, 6th ed.
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