A child with acute osteomyelitis is on appropriate antibiotics. Which laboratory marker is preferred for monitoring treatment response because it normalises fastest?
- A ESR
- B CRP ✓
- C Serum alkaline phosphatase
- D Peripheral blood WBC count
Correct answer: B. CRP
Explanation
CRP rises within hours, peaks around 48 hours, and falls rapidly once infection is controlled, usually normalising within 1 to 2 weeks, making it the best marker for tracking response. ESR rises over days and remains elevated for weeks even after successful treatment, so it cannot be used to judge early resolution. WBC counts may be normal throughout the illness.
Reference: Nelson Textbook of Pediatrics, 21st ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.