A 12-year-old boy presents with dull pain and mild swelling over the mandible for several months. There is no fever. X-ray shows marked cortical thickening and sclerosis of the jaw without a sequestrum. Biopsy shows chronic nonspecific inflammation. Which variant of osteomyelitis is this?

• A Brodie's abscess
• B Tuberculous osteomyelitis
• C Sclerosing osteomyelitis of Garre ✓
• D Ewing sarcoma

Explanation

Garre's sclerosing osteomyelitis is a chronic, non-suppurative form seen typically in the mandible of adolescents, characterised by intense reactive sclerosis and cortical thickening without pus, sequestrum, or sinus formation. It is a reaction to low-virulence organisms or mild trauma. Brodie's abscess is a localised lytic cavity with a sclerotic rim, and Ewing sarcoma shows onion-skin periosteal reaction rather than uniform sclerosis.

Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.

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Written and medically reviewed by the StethoPrep medical team.