A 12-year-old boy presents with progressive painless swelling of the mandible. Radiograph shows massive fusiform cortical thickening and dense sclerosis with no sequestrum, no sinus, and minimal periosteal reaction. Biopsy shows chronic non-specific inflammation. The most appropriate diagnosis is:

• A Fibrous dysplasia
• B Ewing sarcoma
• C Sclerosing osteomyelitis of Garré ✓
• D Osteoid osteoma

Explanation

Garré's sclerosing osteomyelitis is a form of chronic osteomyelitis seen mainly in adolescents, usually in the mandible, characterised by pronounced reactive bone formation producing dense sclerosis and cortical expansion without sequestration or suppuration. Ewing sarcoma produces onion skin periosteal reaction and systemic symptoms. Osteoid osteoma has a radiolucent nidus with night pain relieved by salicylates, neither of which is present here.

Reference: Apley and Solomon's System of Orthopaedics and Trauma, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.