Orthopedics · Bone and Joint Infections (Osteomyelitis, Septic Arthritis)

In a neonate with septic arthritis of the hip, the most common causative organism and the clinical feature that distinguishes neonatal septic arthritis from Perthes disease on ultrasound is:

  • A Staphylococcus aureus; joint effusion with synovial thickening on ultrasound vs. avascular fragmentation in Perthes
  • B Group B Streptococcus; metaphyseal irregularity on X-ray
  • C E. coli; lack of effusion on ultrasound
  • D Candida; bilateral joint involvement
Correct answer: A. Staphylococcus aureus; joint effusion with synovial thickening on ultrasound vs. avascular fragmentation in Perthes

Explanation

Staphylococcus aureus is the most common causative organism of septic arthritis across all age groups including neonates, though neonates (especially premature) also have Group B Streptococcus and Gram-negative organisms (E. coli, Klebsiella) as frequent pathogens. Ultrasound is the investigation of choice in the neonate: it demonstrates hip joint effusion with synovial thickening and increased echogenicity of the joint fluid, which mandates emergency aspiration and surgical irrigation — the definitive diagnostic and therapeutic procedure. Perthes disease (avascular necrosis of the femoral head) is rare under age 4 and shows avascular fragmentation on radiographs (Catterall stages) but no effusion or systemic signs of infection.

Reference: Maheshwari Essential Orthopaedics, 6th ed.

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