A 12-year-old boy with severe hemophilia A has recurrent hemarthroses despite factor VIII prophylaxis. Chronic repetitive bleeding into a joint leads to hemophilic arthropathy. What is the most commonly affected joint in hemophilic arthropathy?
- A Shoulder
- B Knee ✓
- C Hip
- D Ankle
Correct answer: B. Knee
Explanation
The knee is the most commonly affected joint in hemophilic arthropathy, followed by the elbow, ankle, hip, and shoulder. Repetitive hemarthrosis leads to synovial hypertrophy, cartilage destruction, and eventual joint deformity. Prophylactic factor replacement reduces the frequency of bleeds and slows arthropathy progression.
Reference: Hoffbrand's Postgraduate Haematology, 7th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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