A 15-year-old boy with severe hemophilia A presents with recurrent episodes of painful swelling of the right knee requiring factor VIII replacement. Which joint is most commonly affected in hemophilic arthropathy, and what is the term used for this pattern?

• A Knee joint, target joint ✓
• B Ankle joint, complex joint
• C Elbow joint, primary joint
• D Hip joint, index joint

Explanation

The knee is the most common target joint in hemophilic arthropathy, followed by elbows and ankles. Target joint refers to a joint with recurrent hemarthroses occurring at least 3 times in 6 months. Early prophylaxis with factor replacement prevents joint damage and arthropathy.

Reference: Nelson Textbook of Pediatrics, 21st ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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