Ophthalmology · Vitreoretinal Surgery and Diabetic Retinopathy Management — Advanced

A surgeon plans a long-acting expansile gas tamponade following vitrectomy for a recurrent retinal detachment. The gas chosen will be delivered at its non-expansile concentration. What is the approximate non-expansile concentration of C3F8?

  • A About 14 percent
  • B About 5 percent
  • C About 30 percent
  • D About 60 percent
Correct answer: A. About 14 percent

Explanation

C3F8 expands roughly 4 times its volume over several days, so mixing it to approximately 14 percent makes the final bubble non-expansile while retaining its long intraocular life of up to 6 to 8 weeks. Pure C3F8 would expand dangerously and raise intraocular pressure. SF6, by contrast, doubles in volume and its non-expansile mixture is around 18 to 20 percent, which eliminates option B.

Reference: Kanski's Clinical Ophthalmology, 9th ed.

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