According to the International Classification of Retinopathy of Prematurity (ICROP), 'Plus disease' is defined by which finding?
- A Posterior pole venous dilatation and arteriolar tortuosity ✓
- B Avascular retina extending into zone II
- C Neovascularisation at the ridge
- D Vitreous haemorrhage obscuring the posterior pole
Correct answer: A. Posterior pole venous dilatation and arteriolar tortuosity
Explanation
Plus disease, in ICROP, is defined as abnormal dilation of retinal veins and tortuosity of arterioles in the posterior pole (at least 2 quadrants), reflecting increased flow through the abnormal vasculature. It denotes disease activity and worsens prognosis. Avascular retina describes zonal location. Neovascularisation describes Stage 3 disease. Vitreous haemorrhage is a complication. Plus disease can accompany any stage and its presence mandates treatment.
Reference: Khurana Comprehensive Ophthalmology, 7th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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