Ophthalmology · Vitreoretinal Surgery and Diabetic Retinopathy Management — Advanced

Perfluorocarbon liquids (PFCL) are used intraoperatively during vitreoretinal surgery. The primary intraoperative purpose of PFCL in the management of giant retinal tears is:

  • A To act as long-term tamponade after surgery
  • B To flatten and stabilise the retina intraoperatively so that laser or cryotherapy can be applied
  • C To lyse subretinal haemorrhage by chemical action
  • D To lower intraocular pressure during surgery
Correct answer: B. To flatten and stabilise the retina intraoperatively so that laser or cryotherapy can be applied

Explanation

PFCLs are heavy liquids (specific gravity ~1.76–1.94) that displace subretinal fluid posteriorly and mechanically flatten the retina against the RPE during surgery. This allows safe application of endolaser photocoagulation around breaks and prevents retinal re-mobilisation. PFCLs are not left long-term (retinal toxicity); they do not lyse haemorrhage or primarily lower IOP.

Reference: Khurana Comprehensive Ophthalmology, 7th ed.

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