In a patient with any anatomical type of non-infectious uveitis, what is the most common cause of permanent visual loss?
- A Optic nerve atrophy from papillitis
- B Retinal detachment
- C Cystoid macular edema ✓
- D Band-shaped keratopathy
Correct answer: C. Cystoid macular edema
Explanation
Cystoid macular edema caused by breakdown of the blood-retinal barrier is the leading cause of vision impairment in uveitis across all anatomical subtypes. It may be present even when inflammation appears controlled, so OCT should be part of assessment. Retinal detachment, optic atrophy, and band keratopathy all occur but account for a smaller share of vision loss.
Reference: American Academy of Ophthalmology Basic and Clinical Science Course, Section 9: Intraocular Inflammation and Uveitis, 2022-2023 ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.