Why is a cycloplegic such as homatropine prescribed alongside topical steroids in acute anterior uveitis?
- A To lower intraocular pressure by improving aqueous outflow
- B To prevent formation of posterior synechiae and relieve pain from ciliary muscle spasm ✓
- C To reduce corneal oedema by dehydrating the stroma
- D To enhance penetration of the topical corticosteroid into the anterior chamber
Correct answer: B. To prevent formation of posterior synechiae and relieve pain from ciliary muscle spasm
Explanation
Inflamed fibrinous aqueous makes the iris adhere to the anterior lens capsule; cycloplegia keeps the pupil dilated and mobile, breaking and preventing posterior synechiae. Paralysing the ciliary body also abolishes the spasm responsible for deep-seated pain and photophobia. Cycloplegics do not improve outflow, do not dehydrate the cornea, and any effect on drug penetration is incidental and not the therapeutic goal.
Reference: Khurana Comprehensive Ophthalmology, 7th ed.
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Written and medically reviewed by the StethoPrep medical team.