What is the most common pattern of ocular involvement in acquired (secondary) syphilis?

• A Posterior uveitis or panuveitis ✓
• B Isolated acute anterior uveitis without posterior segment disease
• C Interstitial keratitis occurring alone in adults
• D Central retinal artery occlusion with papillitis

Explanation

Syphilis is called the great mimicker because it can involve any ocular structure, but the most frequent presentation of ocular syphilis is posterior uveitis or panuveitis, often with vitritis, chorioretinitis, and retinal vasculitis. Isolated anterior uveitis occurs but is less typical, and interstitial keratitis is chiefly a feature of congenital syphilis. Diagnosis relies on treponemal tests such as FTA-ABS, and treatment is parenteral penicillin G.

Reference: Yanoff and Duker, Ophthalmology, 5th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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