Which category of juvenile idiopathic arthritis carries the highest risk of developing chronic, frequently asymptomatic anterior uveitis?
- A Oligoarticular JIA with positive antinuclear antibodies ✓
- B Systemic-onset JIA
- C Polyarticular JIA with positive rheumatoid factor
- D Enthesitis-related arthritis
Correct answer: A. Oligoarticular JIA with positive antinuclear antibodies
Explanation
Oligoarticular JIA, especially in a young girl who is ANA positive, carries the highest risk of chronic insidious anterior uveitis, which is often silent because the eye stays white and the child reports no symptoms. This is why regular slit-lamp screening every 3 months is mandatory. Systemic-onset JIA almost never causes uveitis, and enthesitis-related arthritis produces an acute symptomatic HLA-A27 anterior uveitis instead.
Reference: Kanski's Clinical Ophthalmology, 9th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.