On fluorescein angiography, a well-defined area of hyperfluorescence that increases in size AND intensity from early to late frames is called:
- A Window defect (transmission hyperfluorescence)
- B Leakage ✓
- C Staining
- D Pooling
Correct answer: B. Leakage
Explanation
Leakage on FFA is characterized by hyperfluorescence that increases in both size and intensity over time due to fluorescein escaping from incompetent vessels into surrounding tissue. Window defect shows hyperfluorescence of fixed size and intensity (no increase). Staining involves fluorescein retained in fibrous or scarred tissue — increases in intensity but not appreciably in size. Pooling occurs when fluorescein accumulates in an anatomical space (e.g., sub-RPE or subretinal space) — increases in intensity, variably in size.
Reference: Khurana Comprehensive Ophthalmology, 7th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.