On fluorescein angiography, the late phase (10 minutes) shows persistent hyperfluorescence due to leakage of dye into the subretinal space with pooling. This is distinguished from 'staining' because staining shows:

• A Persistent fluorescence without increase in size or leakage beyond tissue margins ✓
• B Persistent fluorescence with increasing intensity and size over time
• C Fluorescence that fades progressively after the venous phase
• D Fluorescence confined to the intravascular compartment only

Explanation

Staining refers to slow, persistent hyperfluorescence of tissue without progressive leakage or increase in size, as dye binds to tissue. Pooling (the described subretinal accumulation) shows progressive increase in size and intensity. The distinction between staining and pooling is fundamental to FFA interpretation.

Reference: Ryan's Retina, 6th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.