In optical coherence tomography (OCT) of the retinal nerve fiber layer (RNFL) for glaucoma diagnosis, which quadrant's RNFL thickness is typically the thickest in a normal eye?

• A Superior
• B Temporal
• C Nasal
• D Inferior ✓

Explanation

The inferior RNFL is the thickest in a normal eye, followed by the superior, nasal, and temporal quadrants (ISNT rule: Inferior > Superior > Nasal > Temporal). Loss of the ISNT rule (e.g., superior or nasal thicker than inferior) is an early indicator of glaucomatous damage.

Reference: Bowling, Kanski's Clinical Ophthalmology, 8th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.