During fundus fluorescein angiography of a patient with suspected retinal vasculitis, which finding is most specific for active perivascular inflammation?
- A Perivascular staining and leakage ✓
- B Neovascularization
- C Capillary non-perfusion
- D Venous filling delay
Correct answer: A. Perivascular staining and leakage
Explanation
Perivascular staining and leakage of fluorescein dye in the late phases indicates breakdown of the blood-retinal barrier due to active inflammation. Capillary non-perfusion and venous filling delay indicate secondary ischemia. Neovascularization shows late leakage but represents a secondary proliferative response to ischemia rather than active inflammation itself.
Reference: AAO BCSC Section 12: Retina and Vitreous, 2022-2023 ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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