The most common adverse reaction following intravenous fluorescein injection for fundus angiography is:

• A Anaphylaxis
• B Nausea and vomiting ✓
• C Skin and urine discoloration lasting several days
• D Bronchospasm

Explanation

Nausea, sometimes with vomiting, occurs in roughly 5 to 10 percent of patients and is the commonest adverse effect of fluorescein injection. Anaphylaxis is rare, on the order of 1 in 2000 or less, though it can be life threatening. Yellowish skin and urine discoloration is expected and benign, resolving within 24 to 48 hours, and bronchospasm is uncommon. Patients should be warned about nausea before the test since it typically begins within seconds of injection.

Reference: Kanski's Clinical Ophthalmology, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.