Indocyanine green angiography (ICGA) is SUPERIOR to fluorescein angiography for imaging which of the following?

• A Classic choroidal neovascularisation
• B Disc leakage in papillitis
• C Macular ischaemia in diabetic retinopathy
• D Occult choroidal neovascularisation and polypoidal choroidal vasculopathy ✓

Explanation

ICG dye binds to plasma proteins (97%) and therefore stays within choroidal vessels longer, allowing visualisation of choroidal circulation. ICGA is superior for detecting occult CNV (poorly defined on FFA) and polypoidal choroidal vasculopathy, where polypoid dilatations of the inner choroidal vessels are clearly delineated as nodular hyperfluorescent lesions in early–middle phases. FFA with its high aqueous fluorescence is better for detecting disc leakage and macular ischaemia. Classic CNV is well seen on both modalities.

Reference: Khurana Comprehensive Ophthalmology, 7th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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