On OCT angiography of a patient with wet age-related macular degeneration, a neovascular network is detected in the outer retina/sub-RPE slab. Which OCT-A flow slab is most relevant for detecting type 1 (sub-RPE) choroidal neovascularisation?

• A Superficial capillary plexus
• B Deep capillary plexus
• C Nerve fibre layer slab
• D Outer retina to choriocapillaris (ORCC) slab ✓

Explanation

Type 1 CNV grows beneath the RPE, and OCT-A detection requires the outer retina to choriocapillaris (ORCC) slab which spans from Bruch's membrane through the choriocapillaris. The superficial and deep capillary plexus slabs visualise inner retinal vasculature and miss sub-RPE lesions. The nerve fibre layer slab is used for glaucoma monitoring.

Reference: Khurana Comprehensive Ophthalmology, 7th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.