Ophthalmology · Ophthalmic Imaging and Investigations (OCT, FFA, B-scan, Perimetry, Biometry, Topography)

On optical coherence tomography (OCT) of the macula, a patient with central serous chorioretinopathy (CSCR) shows which characteristic finding in the outer retinal layers?

  • A Hyperreflective dots in the inner nuclear layer
  • B Sub-retinal fluid with intact ellipsoid zone (EZ) and RPE undulation/detachment
  • C Disruption of the EZ with intra-retinal fluid
  • D Hyper-reflective epiretinal membrane with tractional retinal detachment
Correct answer: B. Sub-retinal fluid with intact ellipsoid zone (EZ) and RPE undulation/detachment

Explanation

CSCR classically demonstrates sub-retinal fluid (SRF) on OCT with an intact photoreceptor ellipsoid zone and a focal or broad RPE detachment (pigment epithelial detachment) underlying the SRF. The EZ is initially preserved, distinguishing it from wet AMD where the EZ is disrupted. Intra-retinal fluid and ERM are features of other macular conditions.

Reference: Khurana Comprehensive Ophthalmology, 7th ed.

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