Which feature BEST distinguishes idiopathic orbital inflammation (orbital pseudotumour) from orbital lymphoma?

• A Presence of proptosis
• B Occurrence in middle-aged adults
• C Involvement of the lacrimal gland
• D Rapid dramatic response to systemic corticosteroids ✓

Explanation

Idiopathic orbital inflammation is defined by acute onset of painful proptosis with dramatic shrinkage after systemic corticosteroids, though relapse may occur on tapering. Lymphoma is typically painless, indolent, and only partially steroid responsive. Both conditions can involve the lacrimal gland and cause proptosis in middle-aged adults, so these shared features cannot discriminate between the two diagnoses.

Reference: Kanski's Clinical Ophthalmology, 9th ed.

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Written and medically reviewed by the StethoPrep medical team.