Ophthalmology · Oculoplasty and Orbital Disease (Ptosis, Entropion, Thyroid Eye Disease, Orbital Tumors)

A 60-year-old man presents with a salmon-colored, flat conjunctival lesion in the fornix of the right eye. MRI shows a homogeneously enhancing orbital mass with a 'fish-flesh' appearance on cut section. The most likely diagnosis is:

  • A Orbital lymphoma (MALT type)
  • B Orbital melanoma
  • C Orbital metastasis
  • D Orbital inflammatory pseudotumor
Correct answer: A. Orbital lymphoma (MALT type)

Explanation

Orbital lymphoma, most commonly mucosa-associated lymphoid tissue (MALT) lymphoma, classically presents with a salmon-patch conjunctival lesion and homogeneous mass. It is the most common orbital lymphoma subtype. Melanoma is pigmented. Metastasis usually has a known primary. Inflammatory pseudotumor presents with pain and scleritis, not a salmon-colored patch.

Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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