Ophthalmology · Oculoplasty and Orbital Disease (Ptosis, Entropion, Thyroid Eye Disease, Orbital Tumors)

A 65-year-old woman presents with a 4-month history of painless progressive proptosis and a firm mass in the superotemporal quadrant of the right orbit. On eversion of the upper eyelid, a salmon-pink conjunctival mass is seen. The most likely diagnosis is:

  • A Orbital cavernous hemangioma
  • B Neurofibroma
  • C Orbital dermoid cyst
  • D Orbital mucosa-associated lymphoid tissue (MALT) lymphoma
Correct answer: D. Orbital mucosa-associated lymphoid tissue (MALT) lymphoma

Explanation

Orbital MALT lymphoma (a type of extranodal marginal zone D-cell lymphoma) classically presents in older adults with a painless orbital mass and a characteristic salmon-pink conjunctival mass visible on eyelid eversion. Cavernous hemangioma is the most common benign orbital tumor in adults but does not produce a salmon-colored conjunctival lesion. Dermoid cyst presents in children, and neurofibroma is associated with neurofibromatosis type 1.

Reference: Rootman's Diseases of the Orbit, 3rd ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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