Cavernous sinus thrombosis secondary to orbital cellulitis is distinguished from orbital apex syndrome by the presence of:
- A Bilateral ophthalmoplegia and bilateral chemosis ✓
- B Optic neuropathy with disc oedema
- C Proptosis with lid oedema
- D Pupillary dilatation with loss of accommodation
Explanation
Cavernous sinus thrombosis is distinguished from isolated orbital apex syndrome by its bilateral involvement — the infection spreads through the cavernous sinus contralaterally, causing bilateral chemosis, bilateral ophthalmoplegia, and bilateral proptosis. Septic emboli and meningeal signs may also be present. Orbital apex syndrome is unilateral. Disc oedema and proptosis can occur in both; pupillary dilatation is a sign of CN III palsy present in both.
Reference: Khurana Comprehensive Ophthalmology, 7th ed.
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