In phacoemulsification surgery, which IOL material has the LOWEST rate of posterior capsule opacification?
- A Polymethylmethacrylate (PMMA)
- B Hydrogel (hydrophilic acrylic)
- C Hydrophobic acrylic ✓
- D Silicone
Correct answer: C. Hydrophobic acrylic
Explanation
Hydrophobic acrylic IOLs (e.g., AcrySof) have the lowest PCO rates among currently used materials. The tacky surface of hydrophobic acrylic promotes adhesion to the posterior capsule, blocking migration of lens epithelial cells into the visual axis. The sharp posterior optic edge design (360° posterior square edge) also acts as a barrier to cell migration. Hydrophilic (hydrogel) acrylic has the highest PCO rate. Silicone has intermediate rates. PMMA is associated with higher PCO due to its smooth edge and surface.
Reference: Khurana Comprehensive Ophthalmology, 7th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.