A 48-year-old woman with ocular hypertension has a central corneal thickness of 620 micrometres. How does this finding affect her estimated true intraocular pressure and her risk of progression to glaucoma according to the OHTS data?
- A True IOP is higher than measured; progression risk is increased ✓
- B True IOP is lower than measured; progression risk is reduced
- C True IOP is lower than measured; progression risk is increased
- D True IOP is unaffected; CCT has no prognostic value
Correct answer: A. True IOP is higher than measured; progression risk is increased
Explanation
B thicker cornea (620 micrometres) overestimates the true IOP, meaning the actual IOP is higher than measured. In OHTS, a CCT greater than 588 micrometres was paradoxically associated with lower progression risk, but the key concept tested is that thick corneas cause overestimation of IOP. The best distractor confuses the risk association direction.
Reference: Ocular Hypertension Treatment Study (OHTS) Group, Archives of Ophthalmology, 2002 ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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