A 30-year-old woman with bronchial asthma requires topical glaucoma therapy. Which of the following drug classes is contraindicated in this patient?
- A Prostaglandin analogue
- B Topical beta-blocker ✓
- C Carbonic anhydrase inhibitor (topical)
- D Alpha-2 agonist
Correct answer: B. Topical beta-blocker
Explanation
Topical beta-blockers such as timolol are contraindicated in patients with bronchial asthma because systemic absorption can cause bronchospasm via beta-2 receptor blockade. Topical CAIs, prostaglandin analogues, and alpha-2 agonists (with caution due to CNS effects) are safer alternatives. Brimonidine is contraindicated in children under 2 years due to apnea risk.
Reference: Katzung Basic and Clinical Pharmacology, 15th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.