The Collaborative Normal Tension Glaucoma Study (CNTGS) demonstrated that lowering IOP by 30% in normal-tension glaucoma was associated with which outcome?

• A No benefit over observation
• B Complete halting of progression in all patients
• C Significantly slower visual field progression ✓
• D Worsened cup-to-disc ratio

Explanation

CNTGS showed that a 30% IOP reduction (achieved by medical therapy, laser, or surgery) significantly slowed visual field progression in normal-tension glaucoma compared with untreated controls. It did not halt progression in all patients. Central corneal thickness was identified as a confounding factor, as thinner corneas may have led to underestimation of true IOP at enrollment.

Reference: American Journal of Ophthalmology, CNTGS 1998 ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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