In the mechanism of aqueous outflow, uveoscleral pathway accounts for approximately what percentage of total aqueous drainage in young healthy adults?
- A 20–35% ✓
- B 5–10%
- C 40–50%
- D 60–70%
Correct answer: A. 20–35%
Explanation
In young healthy adults, approximately 20–35% of aqueous drainage occurs via the uveoscleral (unconventional) pathway, flowing through the ciliary muscle interstices into the suprachoroidal space. This proportion decreases with age. Prostaglandin analogues (latanoprost, travoprost, bimatoprost) work primarily by enhancing uveoscleral outflow. The conventional trabecular–Schlemm's canal pathway accounts for the remaining 65–80% of drainage.
Reference: Khurana Comprehensive Ophthalmology, 7th ed.
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