A patient with POAG on maximal medical therapy has persistent IOP of 22 mmHg. According to the AGIS (Advanced Glaucoma Intervention Study), the target IOP to prevent visual field progression should be:
- A Below 21 mmHg
- B Below 14 mmHg ✓
- C Below 18 mmHg
- D Below 10 mmHg
Correct answer: B. Below 14 mmHg
Explanation
The AGIS study found that patients who maintained IOP consistently below 14 mmHg at all follow-up visits showed no visual field progression over 8 years. Patients with any visit above 18 mmHg showed progressive field loss. This established the concept of sustained low IOP target rather than a single measurement threshold, guiding current individualized target IOP setting in advanced glaucoma.
Reference: Khurana Comprehensive Ophthalmology, 7th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.