The OHTS (Ocular Hypertension Treatment Study) demonstrated that topical ocular hypotensive therapy reduced the 5-year risk of developing POAG by approximately:
- A 20%
- B 30%
- C 60% ✓
- D 80%
Correct answer: C. 60%
Explanation
The OHTS showed that medical treatment reducing IOP by approximately 22% cut the 5-year risk of developing POAG from 9.5% (untreated) to 4.4% (treated), representing a ~60% relative risk reduction. The study identified central corneal thickness and cup-to-disc ratio as key risk factors alongside IOP. This trial established the evidence base for treating ocular hypertension in higher-risk patients.
Reference: Khurana Comprehensive Ophthalmology, 7th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.