A patient develops herpes zoster ophthalmicus involving the nasociliary nerve (Hutchinson's sign positive). During which time period is he at highest risk of developing disciform keratitis?

• A 1 to 4 weeks after rash onset ✓
• B Within 1 week of rash onset
• C 2 to 6 months after rash onset
• D 1 year after rash onset

Explanation

Disciform keratitis following herpes zoster ophthalmicus typically presents 1 to 4 weeks after the rash and represents an immune-mediated stromal response rather than active viral replication. The nasociliary nerve involvement carries the highest risk for ocular complications including keratitis.

Reference: Basic and Clinical Science Course, Section 8: External Disease and Cornea, AAO 2023-2024 ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.