A 55-year-old patient presents with painless, progressive bilateral central corneal opacities described as discrete, crumb-like, sharply defined white lesions in the anterior stroma with clear intervening stroma. No vascularization is seen. Which dystrophy is this?
- A Lattice corneal dystrophy
- B Granular corneal dystrophy (type I, Groenouw type I) ✓
- C Macular corneal dystrophy
- D Schnyder crystalline corneal dystrophy
Correct answer: B. Granular corneal dystrophy (type I, Groenouw type I)
Explanation
Granular dystrophy type I shows discrete, sharply demarcated, crumb-like hyaline deposits in the anterior stroma with clear intervening spaces, autosomal dominant inheritance. Lattice dystrophy shows branching linear deposits. Macular dystrophy shows diffuse cloudiness with poorly defined margins throughout the stroma. Schnyder dystrophy shows crystalline deposits with a ring-like pattern.
Reference: Robbins and Cotran Pathologic Basis of Disease, 10th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.