A 24-year-old man presents with bilateral non-ulcerative corneal stromal infiltration with deep neovascularisation, along with progressive sensorineural hearing loss and episodes of vertigo. Which diagnosis fits best?
- A Congenital syphilitic keratitis with labyrinthine disease
- B Cogan syndrome ✓
- C Herpes simplex disciform keratitis with acoustic neuroma
- D Lepromatous interstitial keratitis with cochlear palsy
Correct answer: B. Cogan syndrome
Explanation
Cogan syndrome is non-syphilitic interstitial keratitis combined with vestibuloauditory dysfunction resembling Meniere disease, typically affecting young adults and requiring urgent systemic steroids to prevent deafness. Congenital syphilis presents earlier in life and is accompanied by other stigmata such as Hutchinson teeth and saddle nose.
Reference: Yanoff and Duker Ophthalmology, 6th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.