Which named trial (CAESAR trial) evaluated the effect of uterine closure technique (single-layer vs double-layer) on subsequent uterine scar thickness?

• A CorSu trial
• B VBAC-1 trial
• C ROCSAR trial
• D CAESAR trial ✓

Explanation

The CAESAR (caesarean section surgical techniques) trial was a large multicentre RCT that evaluated different caesarean closure techniques including single- vs double-layer uterine closure, peritoneal closure, and use of adhesion barriers. It found no significant differences in maternal outcomes between techniques, though subsequent observational data suggest double-layer closure may produce thicker uterine scars and lower niche formation rates. The CorSu trial specifically compared continuous vs interrupted single-layer closure and scar niche formation.

Reference: Williams Obstetrics, 26th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.