The peak concentration of Middle Cerebral Artery (MCA) Doppler PSV corresponding to moderate-to-severe fetal anaemia is defined as exceeding what multiples of the median (MoM)?

• A 1.0 MoM
• B 2.0 MoM
• C 0.5 MoM
• D 1.5 MoM ✓

Explanation

MCA-PSV >1.5 MoM for gestational age (Mari et al. threshold) identifies moderate-to-severe fetal anaemia with a sensitivity of >90% and false-positive rate of 12%. This has replaced amniocentesis and serial amniotic fluid bilirubin (Liley curve) as the primary non-invasive screening method. Values >1.5 MoM prompt cordocentesis for haematocrit confirmation and potential transfusion. Values <1.5 MoM are reassuring for fetal anaemia.

Reference: Williams Obstetrics, 26th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

Written and medically reviewed by the StethoPrep medical team.