The SISTER trial (2004) compared which two surgical procedures for stress urinary incontinence and found equivalent continence rates at 2 years?

• A TVT (tension-free vaginal tape) vs. TOT (transobturator tape)
• B Burch colposuspension vs. TVT
• C Burch colposuspension vs. autologous rectus fascial pubovaginal sling ✓
• D Periurethral bulking injection vs. pubovaginal sling

Explanation

The SISTER trial (Stress Incontinence Surgical Treatment Efficacy trial, NEJM 2007) randomised women with stress urinary incontinence to either Burch colposuspension or autologous fascial pubovaginal sling (rectus fascia). Both procedures achieved similar overall success rates (defined as negative pad test + no retreatment) at 24 months (~47% vs. 38%), with sling slightly superior for overall composite success but more voiding dysfunction. TVT vs. TOT was the SISTEr successor; this trial focused on open procedures.

Reference: Shaw's Textbook of Gynaecology, 17th ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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