Obstetrics & Gynaecology · Pelvic Inflammatory Disease and Genital Tuberculosis

A 24-year-old woman at 11 weeks of gestation is diagnosed with mild-to-moderate pelvic inflammatory disease and requires inpatient parenteral therapy. Per CDC 2021 guidance, the appropriate regimen is:

  • A Intravenous ceftriaxone plus azithromycin
  • B Intravenous cefoxitin plus oral doxycycline
  • C Oral moxifloxacin monotherapy
  • D Intravenous clindamycin plus oral doxycycline
Correct answer: A. Intravenous ceftriaxone plus azithromycin

Explanation

Pregnant women with suspected PID must be hospitalised and treated with parenteral cephalosporin plus azithromycin, since tetracyclines are contraindicated in pregnancy because of tooth discoloration and effects on fetal bone, eliminating options B and D. Fluoroquinolones such as moxifloxacin are avoided in pregnancy. Azithromycin is the macrolide of choice and is safe throughout gestation.

Reference: CDC Sexually Transmitted Infections Treatment Guidelines, 2021 ed.

High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP

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