According to the CDC 2021 STI Treatment Guidelines, what is the recommended single intramuscular dose of ceftriaxone for outpatient treatment of mild-to-moderate pelvic inflammatory disease?
- A 125 mg
- B 250 mg
- C 500 mg ✓
- D 1 gram
Correct answer: C. 500 mg
Explanation
The CDC 2021 guidelines raised the ceftriaxone dose for PID from 250 mg to 500 mg IM as a single dose, reflecting rising gonococcal minimum inhibitory concentrations. A 1 gram dose is reserved for patients weighing 150 kg or more. The 250 mg dose remains correct for uncomplicated gonococcal cervicitis without PID, which makes it the most tempting distractor for candidates who remember the older figure.
Reference: CDC STI Treatment Guidelines, 2021 ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.