A 25-year-old woman with PID is started on outpatient treatment. Which combination is recommended by CDC 2021 guidelines for outpatient management of PID?
- A Ciprofloxacin 500 mg BD + metronidazole 400 mg TDS for 14 days
- B Azithromycin 1 g orally weekly for 2 weeks alone
- C Amoxicillin-clavulanate 625 mg TDS for 14 days
- D Ceftriaxone 500 mg IM single dose + doxycycline 100 mg oral BD for 14 days + metronidazole 500 mg BD for 14 days ✓
Correct answer: D. Ceftriaxone 500 mg IM single dose + doxycycline 100 mg oral BD for 14 days + metronidazole 500 mg BD for 14 days
Explanation
CDC 2021 recommended outpatient regimen for PID: ceftriaxone 500 mg IM single dose (covers Neisseria gonorrhoeae) plus doxycycline 100 mg orally twice daily for 14 days (covers Chlamydia and other organisms) plus metronidazole 500 mg orally twice daily for 14 days (covers anaerobes and bacterial vaginosis-associated organisms). Fluoroquinolones are no longer recommended for gonorrhoea due to resistance. Azithromycin monotherapy is inadequate.
Reference: Shaw's Textbook of Gynaecology, 17th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
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