CREST study on long-term sequelae of PID found that a single episode of PID increased the risk of ectopic pregnancy by what approximate factor?
- A 10-fold ✓
- B 2-fold
- C 6-fold
- D 15-fold
Explanation
The CREST (Contraceptive and Reproductive Experiences Study) and subsequent studies demonstrated that one episode of PID increases the risk of subsequent ectopic pregnancy approximately 6–10-fold due to tubal scarring, ciliary dysfunction, and partial tubal obstruction that impairs egg transport while allowing sperm passage. After three or more episodes, infertility rates reach ~40% and ectopic risk rises further. The 10-fold increase is the classically cited figure in most major textbooks for tubal ectopic risk after PID.
Reference: Shaw's Textbook of Gynaecology, 17th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.