A 46-year-old woman with heavy menstrual bleeding and a normal pelvis on ultrasound declines hormonal treatment. Haemoglobin is 10.2 g/dL. Which non-hormonal medical option reduces menstrual blood loss and is appropriate for her?
- A Danazol continuously
- B Tranexamic acid during menses ✓
- C GnRH agonist for 6 months
- D Mifepristone daily
Correct answer: B. Tranexamic acid during menses
Explanation
Tranexamic acid is an antifibrinolytic taken only during menstruation; it reduces menstrual blood loss by roughly 40 to 60 percent and is entirely non-hormonal, suiting women who decline hormonal therapy. Danazol and GnRH agonists are hormonal with significant androgenic or hypoestrogenic side effects, and mifepristone is not standard therapy for heavy menstrual bleeding in routine practice.
Reference: Bailey and Love's Short Practice of Surgery, 28th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.