A 16-year-old girl presents with oligomenorrhea since menarche (age 12), acne, and hirsutism. BMI is 31 kg/m². Serum testosterone is elevated, and LH:FSH ratio is 3:1. Pelvic ultrasound shows 13 follicles (2-9 mm) in each ovary. Thyroid function and prolactin are normal. According to the Rotterdam criteria, what is the diagnosis?
- A Non-classical congenital adrenal hyperplasia
- B Polycystic ovary syndrome ✓
- C Ovarian hyperthecosis
- D Cushing syndrome
Correct answer: B. Polycystic ovary syndrome
Explanation
Rotterdam criteria require two of three: oligo/anovulation, clinical/biochemical hyperandrogenism, and polycystic ovaries on ultrasound. She meets all three. In adolescents, both oligomenorrhea and hyperandrogenism are required, and ultrasound criteria are less reliable before 8 years post-menarche, but the diagnosis here is supported by persistent oligomenorrhea plus hyperandrogenism.
Reference: Williams Gynecology, 4th ed.
High-yield for: NEET PGINI-CETNExTFMGEUSMLEPLABMRCP
Written and medically reviewed by the StethoPrep medical team.