A 24-year-old woman has irregular cycles occurring every 40 to 70 days since menarche, hirsutism, and a BMI of 29 kg/m2. Transvaginal ultrasound shows bilateral ovaries with more than 20 follicles of 2 to 9 mm. Serum testosterone is mildly elevated and 17-OHP is normal. Applying the Rotterdam criteria, how many of the three criteria does she fulfil?
- A One
- B Three ✓
- C Two
- D None, ultrasound findings are required to be unilateral
Explanation
The Rotterdam criteria require two of three features: oligo-ovulation or anovulation, clinical or biochemical hyperandrogenism, and polycystic ovarian morphology on ultrasound. This patient has all three: oligomenorrhoea indicating oligo-ovulation, hirsutism with raised testosterone, and ovaries exceeding the follicle number threshold of 12 follicles of 2 to 9 mm per ovary. Normal 17-OHP excludes non-classic congenital adrenal hyperplasia as the mimic.
Reference: Williams Gynecology, 3rd ed.
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